HCID 10359151, compound → HCID 10470701, compound

HRID 1271865Notes

Reaction equation

HRID 1271865 reaction equation
C(OC(=O)[NH:7][C:8]1[CH:13]=[CH:12][CH:11]=[CH:10][C:9]=1[NH:14][C:15]([C:17]1[NH:18][C:19]2[C:24]([CH:25]=1)=[CH:23][C:22]([O:26][CH2:27][CH2:28][O:29][Si](C(C)(C)C)(C)C)=[CH:21][CH:20]=2)=[O:16])(C)(C)C.NC1C=CC=CC=1NC(C1SC2C=CC(OCCO)=CC=2C=1)=O>>[NH2:7][C:8]1[CH:13]=[CH:12][CH:11]=[CH:10][C:9]=1[NH:14][C:15]([C:17]1[NH:18][C:19]2[C:24]([CH:25]=1)=[CH:23][C:22]([O:26][CH2:27][CH2:28][OH:29])=[CH:21][CH:20]=2)=[O:16]

Participants

3

Reactant 2

HCID 10359151HCID 10359151, compoundHCID 69486955HCID 69486955, compound

Product 1

HCID 10470701HCID 10470701, compound

Procedure

was prepared [2-({5-[2-(tert-Butyl-dimethyl-silanyloxy)-ethoxy]-1H-indole-2-carbonyl}-amino)-phenyl]-carbamic acid tert-butyl ester (44) in an analogous manner to that described for the preparation of (39), example 16, step 2; mp. 222–223° C.

Sources & evidence

ORD record
ord-0cbb07f27c0c4b359a1d16354ec0e070
Source dataset
uspto-grants-2007_04
Patent number
US07208491B2

Reaction notes

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