HCID 10427468, compound → HCID 10471540, compound

HRID 1271868Notes

Reaction equation

HRID 1271868 reaction equation
C([O:5][C:6](=[O:35])[CH2:7][O:8][C:9]1[CH:10]=[C:11]2[C:15](=[CH:16][CH:17]=1)[NH:14][C:13]([C:18](=[O:34])[NH:19][C:20]1[CH:25]=[CH:24][CH:23]=[CH:22][C:21]=1[NH:26]C(OC(C)(C)C)=O)=[CH:12]2)(C)(C)C.NC1C=CC=CC=1NC(C1SC2C=CC(OCC(O)=O)=CC=2C=1)=O>>[NH2:26][C:21]1[CH:22]=[CH:23][CH:24]=[CH:25][C:20]=1[NH:19][C:18]([C:13]1[NH:14][C:15]2[C:11]([CH:12]=1)=[CH:10][C:9]([O:8][CH2:7][C:6]([OH:35])=[O:5])=[CH:17][CH:16]=2)=[O:34]

Participants

3

Reactant 2

HCID 10427468HCID 10427468, compoundHCID 69488451HCID 69488451, compound

Product 1

HCID 10471540HCID 10471540, compound

Procedure

was prepared from [2-(2-tert-Butoxycarbonylamino-phenylcarbamoyl)-1H-indol-5-yloxy]-acetic acid tert-butyl ester (50) in an analogous manner to that described for the preparation of (45) example 19, step 2; mp.: >250° C. (decomposition).

Sources & evidence

ORD record
ord-dd02172d4a8b40d9a569a526470710ad
Source dataset
uspto-grants-2007_04
Patent number
US07208491B2

Reaction notes

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