HuagongsheHuagongshe Chemistry Print Report · For research reference only
Trifluoroacetic acid → HCID 69471534, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Trifluoroacetic acid | HCID 6422 | — |
| Reactant | HCID 69473887 | HCID 69473887 | — |
| Reactant | HCID 69474953 | HCID 69474953 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 69471534 | HCID 69471534 | — |
Reaction Steps
N-(2-Amino-ethyl)-N-[(R)-1-(3-benzyl-7-chloro-4-oxo-3,4-dihydro-quinazolin-2-yl)-2-methyl-propyl]-acrylamide: According to the procedure of Example 1d above, (2-{acryloyl-[(R)-1-(3-benzyl-7-chloro-4-oxo-3,4-dihydro-quinazolin-2-yl)-2-methyl-propyl]-amino}-ethyl)-carbamic acid tert-butyl ester was treated with 50% TFA in CH2Cl2 (3 mL) to give the title compound: MS (ES) m/e 439.2 (M+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07208487B2 |
| Source dataset | uspto-grants-2007_04 |
| ORD ID | ord-66f1df6b28454c83a7018addc9362dc1 |
| Source note | uspto-grants-2007_04 |