HuagongsheHuagongshe Chemistry Print Report · For research reference only
7-Chlorothieno[3,2-b]pyridine-2-carboxylic acid → 2-(Azetidin-1-ylcarbonyl)-7-chlorothieno[3,2-b]pyridine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 7-Chlorothieno[3,2-b]pyridine-2-carboxylic acid | HCID 11276033 | — |
| Reactant | Azetidine hydrochloride | HCID 12308726 | — |
| Product | 2-(Azetidin-1-ylcarbonyl)-7-chlorothieno[3,2-b]pyridine | HCID 22143549 | — |
Reaction Steps
was prepared from 7-chloro-thieno[3,2-b]pyridine-2-carboxylic acid and azetidine hydrochloride following Method A. 1H NMR (300 MHz, DMSO-d6) δ 8.72 (1H, d, J=5.1 Hz), 7.96 (1H, s), 7.70 (1H, d, J=5.1 Hz), 4.62 (2H, t, J=7.4 Hz), 4.12 (2H, t, J=7.7 Hz), 2.34 (2H, tt, J=7.4, 7.7 Hz).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07208500B2 |
| Source dataset | uspto-grants-2007_04 |
| ORD ID | ord-862f05be772741fb9de416845845c089 |
| Source note | uspto-grants-2007_04 |