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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1272132Generated: November 2, 2026

Methyl iodide → (4R,9aR)-6-Ethyl-7-methoxymethyl-4-methyl-3,4,9,9a-tetrahydro-1H-2,4a,5-triaza-fluorene-2-carboxylic acid tert-butyl ester

https://huagongshe.com/reaction/1272132

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethyl iodideHCID 6328—
ReactantSodium hydrideHCID 24758—
Reactant(4R,9aR)-6-ethyl-7-hydroxymethyl-4-methyl-3,4,9,9a-tetrahydro-1H-2,4a,5-triaza-fluorene-2-carboxylic acid tert-butyl esterHCID 69359485—
Product(4R,9aR)-6-Ethyl-7-methoxymethyl-4-methyl-3,4,9,9a-tetrahydro-1H-2,4a,5-triaza-fluorene-2-carboxylic acid tert-butyl esterHCID 69360993—

Reaction Steps

This compound was prepared in analogy to example 1, intermediate d) from (4R,9aR)-6-ethyl-7-hydroxymethyl-4-methyl-3,4,9,9a-tetrahydro-1H-2,4a,5-triaza-fluorene-2-carboxylic acid tert-butyl ester, sodium hydride and methyl iodide.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07208494B2
Source datasetuspto-grants-2007_04
ORD IDord-e91e442422b641858cd0d83f52539832
Source noteuspto-grants-2007_04