HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethyl Bromide → (4R,9aR)-6-Cyclopropylmethoxymethyl-7-ethoxymethyl-4-methyl-3,4,9,9a-tetrahydro-1H-2,4a,5-triaza-fluorene-2-carboxylic acid tert-butyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethyl Bromide | HCID 6332 | — |
| Reactant | Sodium hydride | HCID 24758 | — |
| Reactant | 6-Chloro-7-ethoxy-4-methyl-1,2,3,4-tetrahydro-2,4a,5-triaza-fluorene | HCID 18455987 | — |
| Reactant | (4R,9aR)-6-Cyclopropylmethoxymethyl-7-hydroxymethyl-4-methyl-3,4,9,9a-tetrahydro-1H-2,4a,5-triaza-fluorene-2-carboxylic acid tert-butyl ester | HCID 69359857 | — |
| Product | (4R,9aR)-6-Cyclopropylmethoxymethyl-7-ethoxymethyl-4-methyl-3,4,9,9a-tetrahydro-1H-2,4a,5-triaza-fluorene-2-carboxylic acid tert-butyl ester | HCID 69358724 | — |
Reaction Steps
This compound was prepared in analogy to example 1, intermediate d) from (4R,9aR)-6-cyclopropylmethoxymethyl-7-hydroxymethyl-4-methyl-3,4,9,9a-tetrahydro-1H-2,4a,5-triaza-fluorene-2-carboxylic acid tert-butyl ester, sodium hydride and ethyl bromide.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07208494B2 |
| Source dataset | uspto-grants-2007_04 |
| ORD ID | ord-50c0e27975fe4a8e9f5389cb5fc4cecf |
| Source note | uspto-grants-2007_04 |