Isopropyl isocyanate → 2-oxo-4,5,5-trimethyl-3-thiazoline-O-(isopropylcarbamoyl)-oxime

HRID 127217Notes

Reaction equation

[N:1](=[C:3]1[N:7]=[C:6]([CH3:8])[C:5]([CH3:10])([CH3:9])[S:4]1)[OH:2].[CH:11]([N:14]=[C:15]=[O:16])([CH3:13])[CH3:12]>>[CH:11]([NH:14][C:15]([O:2][N:1]=[C:3]1[N:7]=[C:6]([CH3:8])[C:5]([CH3:10])([CH3:9])[S:4]1)=[O:16])([CH3:13])[CH3:12]

Participants

Reactant 2

HCID 61277Isopropyl isocyanate

HCID 859972442-Oxo-4,5,5-trimethyl-3-thiazoline oxime

Product 1

HCID 867375602-oxo-4,5,5-trimethyl-3-thiazoline-O-(isopropylcarbamoyl)-oxime

Procedure

2-oxo-4,5,5-trimethyl-3-thiazoline-oxime was reacted with isopropyl isocyanate as described in Example 4 to yield 2-oxo-4,5,5-trimethyl-3-thiazoline-O-(isopropylcarbamoyl)-oxime, m.p. 114°-116° C.

Sources & evidence

ORD record: ord-a4fd56c987fd4dbeba159e3e9b5ffb12
Source dataset: uspto-grants-1981_03
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04255436

Reaction notes

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