(s)-Tert-butyl 5-methyl-1,2,3-oxathiazolidine-3-carboxylate 2,2-dioxide → HCID 69360390, compound

HRID 1272177Notes

Reaction equation

HRID 1272177 reaction equation
[CH2:1]([O:3][C:4]([C:6]1[NH:17][C:9]2=[N:10][CH:11]=[C:12]([O:14][CH2:15][CH3:16])[CH:13]=[C:8]2[CH:7]=1)=[O:5])[CH3:2].CC(C)([O-])C.[K+].[C:24]([O:28][C:29]([N:31]1[CH2:35][C@H:34]([CH3:36])OS1(=O)=O)=[O:30])([CH3:27])([CH3:26])[CH3:25]>>[CH2:1]([O:3][C:4]([C:6]1[N:17]([CH:34]([CH3:36])[CH2:35][NH:31][C:29]([O:28][C:24]([CH3:27])([CH3:26])[CH3:25])=[O:30])[C:9]2=[N:10][CH:11]=[C:12]([O:14][CH2:15][CH3:16])[CH:13]=[C:8]2[CH:7]=1)=[O:5])[CH3:2]

Participants

4

Reactant 3

HCID 11195739(s)-Tert-butyl 5-methyl-1,2,3-oxathiazolidine-3-carboxylate 2,2-dioxideHCID 23665647Potassium tert-butoxideHCID 69357158HCID 69357158, compound

Product 1

HCID 69360390HCID 69360390, compound

Procedure

This compound was prepared in analogy to Example 3, intermediate j) from 5-ethoxy-1H-pyrrolo[2,3-b]pyridine-2-carboxylic acid ethyl ester, potassium tert-butoxide and (S)-5-methyl-2,2-dioxo-[1,2,3]oxathiazolidine-3-carboxylic acid tert-butyl ester.

Sources & evidence

ORD record
ord-47cdba77b0e54feaad860f0a50e6fa60
Source dataset
uspto-grants-2007_04
Patent number
US07208494B2

Reaction notes

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