Methyl Isocyanate → HCID 86737580, compound

HRID 127229Notes

Reaction equation

[N:1](=[C:3]1[N:7]=[C:6]([C:8]2[CH:13]=[CH:12][C:11]([Cl:14])=[CH:10][CH:9]=2)[C:5]([CH3:16])([CH3:15])[S:4]1)[OH:2].[CH3:17][N:18]=[C:19]=[O:20]>>[CH3:17][NH:18][C:19]([O:2][N:1]=[C:3]1[N:7]=[C:6]([C:8]2[CH:13]=[CH:12][C:11]([Cl:14])=[CH:10][CH:9]=2)[C:5]([CH3:16])([CH3:15])[S:4]1)=[O:20]

Participants

Reactant 2

HCID 12228Methyl Isocyanate

HCID 86737581HCID 86737581, compound

Product 1

HCID 86737580HCID 86737580, compound

Procedure

2-oxo-4-(p-chlorophenyl)-5,5-dimethyl-3-thiazoline-oxime was reacted with methyl isocyanate as described in Example 4 to yield 2-oxo-4-(p-chlorophenyl)-5,5-dimethyl-3-thiazoline-O-(methylcarbamoyl)-oxime, m.p. 147°-149° C. The 2-oxo-4-(p-chlorophenyl)-5,5-dimethyl-3-thiazoline-oxime starting material melts at 205°-207° C.

Sources & evidence

ORD record: ord-50df1e6a324f4997b40c0e54e7a91545
Source dataset: uspto-grants-1981_03
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04255436

Reaction notes

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