HCID 10208568, compound → HCID 10300578, compound

HRID 1272291Notes

Reaction equation

HRID 1272291 reaction equation
[CH3:1][O:2][C:3]1[CH:4]=[C:5]([CH:11]2[CH2:16][C:15](=O)[N:14]([C:18]3[C:19]([CH3:38])=[C:20]([CH3:37])[C:21]4[O:25][C:24]([CH3:27])([CH3:26])[C@H:23]([C:28]5[CH:33]=[CH:32][C:31]([CH3:34])=[CH:30][CH:29]=5)[C:22]=4[C:35]=3[CH3:36])[C:13](=O)[CH2:12]2)[CH:6]=[CH:7][C:8]=1[O:9][CH3:10]>CCCCCC>[CH3:1][O:2][C:3]1[CH:4]=[C:5]([CH:11]2[CH2:12][CH2:13][N:14]([C:18]3[C:19]([CH3:38])=[C:20]([CH3:37])[C:21]4[O:25][C:24]([CH3:27])([CH3:26])[C@H:23]([C:28]5[CH:33]=[CH:32][C:31]([CH3:34])=[CH:30][CH:29]=5)[C:22]=4[C:35]=3[CH3:36])[CH2:15][CH2:16]2)[CH:6]=[CH:7][C:8]=1[O:9][CH3:10]

Participants

3

Reactant 1

HCID 10208568HCID 10208568, compound

Product 1

HCID 10300578HCID 10300578, compoundYield 54%

Reagents, catalysts & solvents 1

HCID 8058HexaneSolvent

Procedure

Using (3R)-4-(3,4-dimethoxyphenyl)-1-(2,2,4,6,7-pentamethyl-3-(4-methylphenyl)-2,3-dihydro-1-benzofuran-5-yl)piperidine-2,6-dione obtained in Example 27, the title compound was synthesized in the same manner as in Example 28. Yield 54%. mp. 102–106° C. (hexane).

Sources & evidence

ORD record
ord-bef207e8624d4480afe58fd33b01d55b
Source dataset
uspto-grants-2007_04
Patent number
US07208495B2

Reaction notes

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