HCID 10120000, compound → HCID 10143308, compound

HRID 1272297Notes

Reaction equation

HRID 1272297 reaction equation
O[C:2]1([C:30]2[CH:35]=[CH:34][C:33]([C:36]3[CH:41]=[CH:40][CH:39]=[CH:38][CH:37]=3)=[CH:32][CH:31]=2)[C:6]2[C:7]([CH3:27])=[C:8]([N:13]3[CH2:18][CH2:17][N:16]([C:19]4[CH:24]=[CH:23][C:22]([O:25][CH3:26])=[CH:21][CH:20]=4)[CH2:15][CH2:14]3)[C:9]([CH3:12])=[C:10]([CH3:11])[C:5]=2[O:4][C:3]1([CH3:29])[CH3:28]>C(O)C>[CH3:28][C:3]1([CH3:29])[CH:2]([C:30]2[CH:31]=[CH:32][C:33]([C:36]3[CH:37]=[CH:38][CH:39]=[CH:40][CH:41]=3)=[CH:34][CH:35]=2)[C:6]2[C:7]([CH3:27])=[C:8]([N:13]3[CH2:14][CH2:15][N:16]([C:19]4[CH:20]=[CH:21][C:22]([O:25][CH3:26])=[CH:23][CH:24]=4)[CH2:17][CH2:18]3)[C:9]([CH3:12])=[C:10]([CH3:11])[C:5]=2[O:4]1

Participants

3

Reactant 1

HCID 10120000HCID 10120000, compound

Product 1

HCID 10143308HCID 10143308, compoundYield 82%

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

Using 1-(3-hydroxy-2,2,4,6,7-pentamethyl-3-(1,1′-biphenyl-4-yl)-2,3-dihydro-1-benzofuran-5-yl)-4-(4-methoxyphenyl)piperazine obtained in Example 35, the title compound was synthesized in the same manner as in Example 46. Yield 82%. mp. 147–148° C. (ethanol).

Sources & evidence

ORD record
ord-e503a3600a9b4e6f8ce2991e02060efb
Source dataset
uspto-grants-2007_04
Patent number
US07208495B2

Reaction notes

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