HCID 10115646, compound → HCID 10160865, compound

HRID 1272299Notes

Reaction equation

HRID 1272299 reaction equation
[O:1]1[CH:5]=[CH:4][C:3]([C:6]2(O)[C:10]3[C:11]([CH3:31])=[C:12]([N:17]4[CH2:22][CH2:21][N:20]([C:23]5[CH:28]=[CH:27][C:26]([O:29][CH3:30])=[CH:25][CH:24]=5)[CH2:19][CH2:18]4)[C:13]([CH3:16])=[C:14]([CH3:15])[C:9]=3[O:8][C:7]2([CH3:33])[CH3:32])=[CH:2]1>CO>[O:1]1[CH:5]=[CH:4][C:3]([CH:6]2[C:10]3[C:11]([CH3:31])=[C:12]([N:17]4[CH2:18][CH2:19][N:20]([C:23]5[CH:28]=[CH:27][C:26]([O:29][CH3:30])=[CH:25][CH:24]=5)[CH2:21][CH2:22]4)[C:13]([CH3:16])=[C:14]([CH3:15])[C:9]=3[O:8][C:7]2([CH3:33])[CH3:32])=[CH:2]1

Participants

3

Reactant 1

HCID 10115646HCID 10115646, compound

Product 1

HCID 10160865HCID 10160865, compoundYield 72%

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

Using 1-(3-(3-furyl)-3-hydroxy-2,2,4,6,7-pentamethyl-2,3-dihydro-1-benzofuran-5-yl)-4-(4-methoxyphenyl)piperazine obtained in Example 37, the title compound was synthesized in the same manner as in Example 46. Yield 72%. mp. 110–113° C. (methanol).

Sources & evidence

ORD record
ord-508a3cfd43e44ea4aeb0739f24c1e690
Source dataset
uspto-grants-2007_04
Patent number
US07208495B2

Reaction notes

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