HCID 10299376, compound → HCID 10204995, compound

HRID 1272303Notes

Reaction equation

HRID 1272303 reaction equation
O[C:2]1([C:30]2[S:31][CH:32]=[CH:33][CH:34]=2)[C:6]2[C:7]([CH3:27])=[C:8]([N:13]3[CH2:18][CH2:17][N:16]([C:19]4[CH:24]=[CH:23][C:22]([O:25][CH3:26])=[CH:21][CH:20]=4)[CH2:15][CH2:14]3)[C:9]([CH3:12])=[C:10]([CH3:11])[C:5]=2[O:4][C:3]1([CH3:29])[CH3:28]>C(O)C>[CH3:28][C:3]1([CH3:29])[CH:2]([C:30]2[S:31][CH:32]=[CH:33][CH:34]=2)[C:6]2[C:7]([CH3:27])=[C:8]([N:13]3[CH2:14][CH2:15][N:16]([C:19]4[CH:20]=[CH:21][C:22]([O:25][CH3:26])=[CH:23][CH:24]=4)[CH2:17][CH2:18]3)[C:9]([CH3:12])=[C:10]([CH3:11])[C:5]=2[O:4]1

Participants

3

Reactant 1

HCID 10299376HCID 10299376, compound

Product 1

HCID 10204995HCID 10204995, compoundYield 78%

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

Using 1-(3-hydroxy-2,2,4,6,7-pentamethyl-3-(2-thienyl)-2,3-dihydro-1-benzofuran-5-yl)-4-(4-methoxyphenyl)piperazine obtained in Example 41, the title compound was synthesized in the same manner as in Example 46. Yield 78%. mp. 139–141° C. (ethanol).

Sources & evidence

ORD record
ord-fa3c3b4c13c6442c9b6d07f9b836507a
Source dataset
uspto-grants-2007_04
Patent number
US07208495B2

Reaction notes

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