HCID 10276486, compound → HCID 10275447, compound

HRID 1272304Notes

Reaction equation

HRID 1272304 reaction equation
[O:1]1[CH:5]=[CH:4][CH:3]=[C:2]1[C:6]1(O)[C:10]2[C:11]([CH3:31])=[C:12]([N:17]3[CH2:22][CH2:21][N:20]([C:23]4[CH:28]=[CH:27][C:26]([O:29][CH3:30])=[CH:25][CH:24]=4)[CH2:19][CH2:18]3)[C:13]([CH3:16])=[C:14]([CH3:15])[C:9]=2[O:8][C:7]1([CH3:33])[CH3:32]>C(O)C>[O:1]1[CH:5]=[CH:4][CH:3]=[C:2]1[CH:6]1[C:10]2[C:11]([CH3:31])=[C:12]([N:17]3[CH2:18][CH2:19][N:20]([C:23]4[CH:28]=[CH:27][C:26]([O:29][CH3:30])=[CH:25][CH:24]=4)[CH2:21][CH2:22]3)[C:13]([CH3:16])=[C:14]([CH3:15])[C:9]=2[O:8][C:7]1([CH3:33])[CH3:32]

Participants

3

Reactant 1

HCID 10276486HCID 10276486, compound

Product 1

HCID 10275447HCID 10275447, compoundYield 67%

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

Using 1-(3-(2-furyl)-3-hydroxy-2,2,4,6,7-pentamethyl-2,3-dihydro-1-benzofuran-5-yl)-4-(4-methoxyphenyl)piperazine obtained in Example 42, the title compound was synthesized in the same manner as in Example 46. Yield 67%. mp. 110–111° C. (ethanol).

Sources & evidence

ORD record
ord-126ec45f4c28414cae1cb9e046e985bf
Source dataset
uspto-grants-2007_04
Patent number
US07208495B2

Reaction notes

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