HCID 58847345, compound → HCID 18456067, compound

HRID 1272325Notes

Reaction equation

HRID 1272325 reaction equation
[CH3:1][O:2][C:3]1[CH:4]=[C:5]([CH:11]2[CH2:16][CH2:15][N:14]([C:17]3[C:18]([CH3:37])=[C:19]([CH3:36])[C:20]4[O:24][C:23]([CH3:26])([CH3:25])[C:22]([C:28]5[CH:33]=[CH:32][CH:31]=[CH:30][CH:29]=5)(O)[C:21]=4[C:34]=3[CH3:35])[CH2:13][CH2:12]2)[CH:6]=[CH:7][C:8]=1[O:9][CH3:10]>C(O)C>[CH3:1][O:2][C:3]1[CH:4]=[C:5]([CH:11]2[CH2:12][CH2:13][N:14]([C:17]3[C:18]([CH3:37])=[C:19]([CH3:36])[C:20]4[O:24][C:23]([CH3:26])([CH3:25])[CH:22]([C:28]5[CH:33]=[CH:32][CH:31]=[CH:30][CH:29]=5)[C:21]=4[C:34]=3[CH3:35])[CH2:15][CH2:16]2)[CH:6]=[CH:7][C:8]=1[O:9][CH3:10]

Participants

3

Reactant 1

HCID 58847345HCID 58847345, compound

Product 1

HCID 18456067HCID 18456067, compoundYield 65%

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

Using 5-(4-(3,4-dimethoxyphenyl)piperidino)-2,2,4,6,7-pentamethyl-3-phenyl-2,3-dihydro-1-benzofuran-3-ol obtained in Example 80, the title compound was synthesized in the same manner as in Example 46. Yield 65%. mp. 118–120° C. (ethanol).

Sources & evidence

ORD record
ord-3b7111548d4c4f37b8b5d3627ee2cf85
Source dataset
uspto-grants-2007_04
Patent number
US07208495B2

Reaction notes

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