HCID 58847350, compound → HCID 22935580, compound

HRID 1272338Notes

Reaction equation

HRID 1272338 reaction equation
[F:1][C:2]1[N:7]=[CH:6][C:5]([C:8]2(O)[C:12]3[C:13]([CH3:32])=[C:14]([N:19]4[CH2:24][CH2:23][N:22]([CH2:25][C:26]5[CH:31]=[CH:30][CH:29]=[CH:28][CH:27]=5)[CH2:21][CH2:20]4)[C:15]([CH3:18])=[C:16]([CH3:17])[C:11]=3[O:10][C:9]2([CH3:34])[CH3:33])=[CH:4][CH:3]=1>CCCCCC>[CH2:25]([N:22]1[CH2:21][CH2:20][N:19]([C:14]2[C:15]([CH3:18])=[C:16]([CH3:17])[C:11]3[O:10][C:9]([CH3:34])([CH3:33])[CH:8]([C:5]4[CH:6]=[N:7][C:2]([F:1])=[CH:3][CH:4]=4)[C:12]=3[C:13]=2[CH3:32])[CH2:24][CH2:23]1)[C:26]1[CH:27]=[CH:28][CH:29]=[CH:30][CH:31]=1

Participants

3

Reactant 1

HCID 58847350HCID 58847350, compound

Product 1

HCID 22935580HCID 22935580, compoundYield 78%

Reagents, catalysts & solvents 1

HCID 8058HexaneSolvent

Procedure

Using 3-(6-fluoropyridine-3-yl)-5-(4-benzylpiperazin-1-yl)-2,2,4,6,7-pentamethyl-2,3-dihydro-1-benzofuran-3-ol obtained in Example 125, the title compound was synthesized in the same manner as in Example 46. Yield 78%. mp. 76–79° C. (hexane).

Sources & evidence

ORD record
ord-96bfe4ea9aaf42cb953b26a7a45c65e8
Source dataset
uspto-grants-2007_04
Patent number
US07208495B2

Reaction notes

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