HCID 58847353, compound → HCID 18456072, compound

HRID 1272349Notes

Reaction equation

HRID 1272349 reaction equation
[CH3:1][O:2][C:3]1[CH:8]=[CH:7][C:6]([N:9]2[CH2:14][CH2:13][N:12]([C:15]3[C:33]([CH3:34])=[C:32]([CH3:35])[C:18]4[C:19]([C:25]5[CH:30]=[CH:29][C:28]([CH3:31])=[CH:27][CH:26]=5)(O)[C:20]([CH3:23])([CH3:22])[O:21][C:17]=4[C:16]=3[CH3:36])[CH2:11][CH2:10]2)=[CH:5][CH:4]=1>C(O)C>[CH3:1][O:2][C:3]1[CH:8]=[CH:7][C:6]([N:9]2[CH2:14][CH2:13][N:12]([C:15]3[C:33]([CH3:34])=[C:32]([CH3:35])[C:18]4[CH:19]([C:25]5[CH:26]=[CH:27][C:28]([CH3:31])=[CH:29][CH:30]=5)[C:20]([CH3:23])([CH3:22])[O:21][C:17]=4[C:16]=3[CH3:36])[CH2:11][CH2:10]2)=[CH:5][CH:4]=1

Participants

3

Reactant 1

HCID 58847353HCID 58847353, compound

Product 1

HCID 18456072HCID 18456072, compoundYield 85%

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

Using 6-(4-(4-methoxyphenyl)piperazin-1-yl)-2,2,4,5,7-pentamethyl-3-(4-methylphenyl)-2,3-dihydro-1-benzofuran-3-ol obtained in Example 140, the title compound was synthesized in the same manner as in Example 46. Yield 85% mp. 160–162° C. (ethanol).

Sources & evidence

ORD record
ord-d93fe4a1fb154eb0adbd9fd734e74abe
Source dataset
uspto-grants-2007_04
Patent number
US07208495B2

Reaction notes

Loading…