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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1272397Generated: October 25, 2026

Aniline → Methanimidic acid, N-phenyl-, ethyl ester

https://huagongshe.com/reaction/1272397

Reaction equation

Participants

RoleNameHCIDCharge
ReactantAnilineHCID 6115—
ReactantEthyl orthoformateHCID 31214—
ReactantN,N'-DiphenylformamidineHCID 94888—
ProductMethanimidic acid, N-phenyl-, ethyl esterHCID 111236—

Reaction Steps

The synthesis is achieved in three steps. The first step is the preparation of N,N′-diphenyl formamidine (by the reaction of aniline with triethyl orthoformate). This intermediate is then further reacted with triethyl orthoformate to produce ethyl N-phenylimidoformate. The final step is the reaction of ethyl phenylimidoformate with 4-aminostyrene to give the product.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07208557B2
Source datasetuspto-grants-2007_04
ORD IDord-1ef5853adf0c4154b000c2a12196db5b
Source noteuspto-grants-2007_04