Bromine → HCID 20286578, compound

HRID 127240Notes

Reaction equation

HRID 127240 reaction equation
[Cl:1][CH2:2][C:3]([CH3:22])([CH3:21])[C:4](=[O:20])[CH2:5][O:6][C:7]1[CH:12]=[CH:11][C:10]([C:13]2[CH:18]=[CH:17][C:16]([Cl:19])=[CH:15][CH:14]=2)=[CH:9][CH:8]=1.[Br:23]Br>C(Cl)(Cl)(Cl)Cl>[Br:23][CH:5]([O:6][C:7]1[CH:12]=[CH:11][C:10]([C:13]2[CH:14]=[CH:15][C:16]([Cl:19])=[CH:17][CH:18]=2)=[CH:9][CH:8]=1)[C:4](=[O:20])[C:3]([CH3:22])([CH3:21])[CH2:2][Cl:1]

Participants

4

Reactant 2

HCID 24408Bromine2×HCID 202865984-Chloro-1-[4-(4-chlorophenyl)-phenoxy]-3,3-dimethyl-butan-2-one

Product 1

HCID 20286578HCID 20286578, compound

Reagents, catalysts & solvents 1

HCID 5943Carbon TetrachlorideSolvent

Procedure

33.7 g (0.1 mol) of 4-chloro-1-[4-(4-chlorophenyl)-phenoxy]-3,3-dimethyl-butan-2-one were dissolved in 250 ml of carbon tetrachloride. 5.1 ml (0.1 mol) of bromine were added dropwise at room temperature at a rate such that the bromine was steadily consumed. The mixture was then stirred for 30 minutes at room temperature. After distilling off the solvent in vacuo, crude 1-bromo-4-chloro-1-[4-(4-chlorophenyl)-phenoxy]3,3-dimethyl-butan-2-one was obtained in quantitative yield and was directly reacted further.

Workup

  1. customwas steadily consumed
  2. distillationAfter distilling off the solvent in vacuo

Sources & evidence

ORD record
ord-8377a53636eb4fd1958c4726490f4365
Source dataset
uspto-grants-1981_03
Patent number
US04255434

Reaction notes

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