反应详情

33.7 g (0.1 mol) of 4-chloro-1-[4-(4-chlorophenyl)-phenoxy]-3,3-dimethyl-butan-2-one were dissolved in 250 ml of carbon tetrachloride. 5.1 ml (0.1 mol) of bromine were added dropwise at room temperature at a rate such that the bromine was steadily consumed. The mixture was then stirred for 30 minutes at room temperature. After distilling off the solvent in vacuo, crude 1-bromo-4-chloro-1-[4-(4-chlorophenyl)-phenoxy]3,3-dimethyl-butan-2-one was obtained in quantitative yield and was directly reacted further.

1. customwas steadily consumed
2. distillationAfter distilling off the solvent in vacuo