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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1272413Generated: October 29, 2026

tert-butyl N-[2-(2-benzyloxy-4-isopropylphenyl)ethyl]carbamate → 2-(2-Benzyloxy-4-isopropylphenyl)ethylamine hydrochloride

https://huagongshe.com/reaction/1272413

Reaction equation

Participants

RoleNameHCIDCharge
Reactanttert-butyl N-[2-(2-benzyloxy-4-isopropylphenyl)ethyl]carbamateHCID 18457007—
ReactantEthanol hydrochlorideHCID 21887872—
SolventEthanolHCID 702—
Product2-(2-Benzyloxy-4-isopropylphenyl)ethylamine hydrochlorideHCID 17856229—

Reaction Steps

To a solution of 0.300 g of tert-butyl N-[2-(2-benzyloxy-4-isopropylphenyl)ethyl]carbamate in 2 mL of ethanol was added 2 mL of 21% hydrogen chloride ethanol solution at room temperature. After being stirred at the same temperature for 2 hours, the reaction mixture was concentrated under reduced pressure to give 0.261 g of 2-(2-benzyloxy-4-isopropylphenyl)ethylamine hydrochloride.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07208524B2
Source datasetuspto-grants-2007_04
ORD IDord-3bffe121e1684cd1962bd3c987b62933
Source noteuspto-grants-2007_04