HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Dopac → 2-(3,4-Dihydroxy-phenyl)-N-[2-(1H-indol-2-yl)-phenyl]-acetamide
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Dopac | HCID 547 | — |
| Edukt | 2-(2-Aminophenyl)indole | HCID 735966 | — |
| Produkt | 2-(3,4-Dihydroxy-phenyl)-N-[2-(1H-indol-2-yl)-phenyl]-acetamide | HCID 10247810 | 17% |
Reaktionsschritte
Prepared from 2-(2-aminophenyl) indole and 3,4-dihydroxyphenylacetic acid in 17% yield. The product was chromatographed on silica. 100% Purity by LC/MS (230 DAD), Mass-spec [M+H+]=359, 1H NMR (MeOH-d4): 3.56 s (2H), 6.10 s (1H), 6.59 dd, 8, 2 Hz (1H), 6.66 d, 8 Hz (1H), 6.78 d, 2 Hz (1H), 7.03 t, 8 Hz (1H), 7.11 t, 8 Hz (1H), 7.25 t, 8 Hz (1H), 7.31–7.35 m (2H), 7.51 d, 7 Hz (1H), 7.55 dd, 8.1 Hz (1H), 7.99 d, 8 Hz (1H).
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US07208493B2 |
| Quelldatensatz | uspto-grants-2007_04 |
| ORD ID | ord-530ff530aed44411a635bc0f9e4a523a |
| Quellennotiz | uspto-grants-2007_04 |