HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Fluorobenzyl chloride → 1-(4-Fluorobenzyl)-4-(2-hydroxy-3-n-hexadecyloxypropyl)-piperazine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Fluorobenzyl chloride | HCID 9602 | — |
| Reactant | 1-(2-Hydroxy-3-n-hexadecyloxypropyl)-piperazine | HCID 13037790 | — |
| Product | 1-(4-Fluorobenzyl)-4-(2-hydroxy-3-n-hexadecyloxypropyl)-piperazine | HCID 13037797 | — |
Reaction Steps
Following the procedure of Example 5, 1-(2-hydroxy-3-n-hexadecyloxypropyl)-piperizine was reacted with 4-fluorobenzyl chloride to form 1-(4-fluorobenzyl)-4-(2-hydroxy-3-n-hexadecyloxypropyl)-piperazine, mp 242° C. (dec).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04255426 |
| Source dataset | uspto-grants-1981_03 |
| ORD ID | ord-f18ca96baa2a4263949e5f2e951a18b5 |
| Source note | uspto-grants-1981_03 |