HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Fluorobenzyl chloride → HCID 13037800, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Fluorobenzyl chloride | HCID 9602 | — |
| Reactant | HCID 13037799 | HCID 13037799 | — |
| Reactant | HCID 20553812 | HCID 20553812 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Product | HCID 13037800 | HCID 13037800 | — |
Reaction Steps
Following the procedures of Examples 4 and 5, 1-benzyl-4-(2-hydroxy-3-n-dodecyloxypropyl)-piperazine was converted to 1-(2-hydroxy-3-n-dodecyloxypropyl)piperazine by hydrogenolysis using a palladium on carbon catalyst. The hydrogenolysis product was reacted with 4-fluorobenzyl chloride to form 1-(4-fluorobenzyl)-4-(2-hydroxy-3-n-dodecyloxypropyl)-piperazine, mp 243°-245° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04255426 |
| Source dataset | uspto-grants-1981_03 |
| ORD ID | ord-962c7848b81e4762a497e941bb1a4c4e |
| Source note | uspto-grants-1981_03 |