HRID127261

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID199815

1-Oxa-3,8-diazaspiro(4.5)decan-2-one, 8-benzyl-

C14H18N2O2

PRODUCTS

生成物

HCID12954114

1-Oxa-3,8-diazaspiro[4.5]decan-2-one

C7H12N2O2

收率 106.8%

AUXILIARIES

试剂、催化剂与溶剂

催化剂HCID23938

Palladium

溶剂HCID702

Ethanol

C2H6O

PROCEDURE

实验过程

A mixture of 6.2 g 8-benzyl-1-oxa-3,8-diazaspiro[4.5]decan-2-one, 50 ml ethanol and 0.5 g, 10% palladium on carbon is hydrogenated at 60 psi and 50° for 18 hours. After filtration and removal of solvent there is obtained 4.2 g 1-oxa-3,8-diazaspiro[4.5]decan-2-one, mp 158°-161°.

WORKUP

后处理

filtrationAfter filtration and removal of solvent