HuagongsheHuagongshe Chemistry Print Report · For research reference only
Cyclopentylacetic acid → 2-(2-Cyclopentyl-acetylamino)-3-(3-hydroxy-phenyl)-propionic acid methyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Cyclopentylacetic acid | HCID 71606 | — |
| Reactant | Methyl 2-amino-3-(3-hydroxyphenyl)propanoate | HCID 22386100 | — |
| Product | 2-(2-Cyclopentyl-acetylamino)-3-(3-hydroxy-phenyl)-propionic acid methyl ester | HCID 68871419 | 54.9% |
Reaction Steps
12.5 g (54.3 mmol) of 2-amino-3-(3-hydroxy-phenyl)-propionic acid methyl ester was reacted with cyclopentyl acetic acid (6.97 g, 54.3 mmol) as described in general procedure A. The compound was purified using gradient elution with ethyl acetate in hexanes to yield 9.1 g of 2-(2-cyclopentyl-acetylamino)-3-(3-hydroxy-phenyl)-propionic acid methyl ester.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07208601B2 |
| Source dataset | uspto-grants-2007_04 |
| ORD ID | ord-494cabc8625d40c5afb7d8e765fef5a6 |
| Source note | uspto-grants-2007_04 |