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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1272749Generated: October 30, 2026

Lithium hydroxide, monohydrate → HCID 22479866, compound

https://huagongshe.com/reaction/1272749

Reaction equation

Participants

RoleNameHCIDCharge
ReactantLithium hydroxide, monohydrateHCID 168937—
ReactantHCID 22480251HCID 22480251—
SolventTetrahydrofuranHCID 8028—
ProductHCID 22479866HCID 2247986670.5%

Reaction Steps

The title compound was prepared using methyl 4-[N-(3-(4-pyridyl)-1H-indazol-5-yl)carbamoyl]benzoate (0.129 g, 0.35 mmol) and lithium hydroxide mono hydrate (0.075 g, 1.8 mmol) in tetrahydrofuran (5 mL). The compound was isolated as a beige powder that was washed with small portions of diethyl ether (5 mL). (0.091 g, 70.5% yield) 1H NMR (DMSO-d6) 10.2 (s, 1H), 8.5 (m, 3H), 7.9–7.8 (m, 6H), 7.6 (s, 2H); ES-MS (m/z) 359 [M+1]+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07208513B2
Source datasetuspto-grants-2007_04
ORD IDord-bc9d571d23c74de2adf992715a7a1438
Source noteuspto-grants-2007_04