HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Aminopyridine → HCID 12650513, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Aminopyridine | HCID 10009 | — |
| Reactant | Cyclopentane-1,1-diacetic anhydride | HCID 79743 | — |
| Solvent | O-Xylene | HCID 7237 | — |
| Product | HCID 12650513 | HCID 12650513 | — |
Reaction Steps
The starting material is prepared as follows. The mixture of 16.8 g of 3,3-tetramethyleneglutaric anhydride, 9.4 g of 3-aminopyridine and 225 ml of xylene is stirred and refluxed for 48 hours while collecting the water formed. After cooling in the refrigerator the precipitate obtained is filtered off and recrystallized from 300 ml ethanol-hexane, to yield the 8-(3-pyridyl)-8-azaspiro[4,5]decan-7,9-dione melting at 153°-154°.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04255429 |
| Source dataset | uspto-grants-1981_03 |
| ORD ID | ord-2f1c898da73c49e6806d3c06b02b64ab |
| Source note | uspto-grants-1981_03 |