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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1273085Generated: October 30, 2026

Indomethacin → HCID 178487187, compound

https://huagongshe.com/reaction/1273085

Reaction equation

Participants

RoleNameHCIDCharge
ReactantIndomethacinHCID 3715—
Reactant4-Amino-2-(trifluoromethyl)benzonitrileHCID 522170—
Reagent1-MethylimidazoleHCID 1390—
ReagentHCID 178483690HCID 178483690—
SolventAcetonitrileHCID 6342—
ProductHCID 178487187HCID 17848718710.75%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

DOI10.26434/chemrxiv
Source datasetAniline amide coupling reaction
ORD IDord-028b4c4afef94d93b275a1fd3ac506e4
Source noteAniline amide coupling reaction