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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1273108Generated: November 1, 2026

Indomethacin → HCID 178487187, compound

https://huagongshe.com/reaction/1273108

Reaction equation

Participants

RoleNameHCIDCharge
ReactantIndomethacinHCID 3715—
Reactant4-Amino-2-(trifluoromethyl)benzonitrileHCID 522170—
ReagentDiisopropylethylamineHCID 81531—
ReagentPyBOPHCID 2724699—
SolventTetrahydrofuranHCID 8028—
ProductHCID 178487187HCID 1784871870.86%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

DOI10.26434/chemrxiv
Source datasetAniline amide coupling reaction
ORD IDord-f6365a7b02bc4a71aee22bb64a7ebb37
Source noteAniline amide coupling reaction