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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1273109Generated: November 2, 2026

Indomethacin → HCID 178487187, compound

https://huagongshe.com/reaction/1273109

Reaction equation

Participants

RoleNameHCIDCharge
ReactantIndomethacinHCID 3715—
Reactant4-Amino-2-(trifluoromethyl)benzonitrileHCID 522170—
Reagent1-MethylimidazoleHCID 1390—
ReagentPyBOPHCID 2724699—
SolventAcetonitrileHCID 6342—
ProductHCID 178487187HCID 1784871871.84%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

DOI10.26434/chemrxiv
Source datasetAniline amide coupling reaction
ORD IDord-5a5e84ec82f74f90b34c9ea163338110
Source noteAniline amide coupling reaction