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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1273110Generated: November 3, 2026

Indomethacin → HCID 178487187, compound

https://huagongshe.com/reaction/1273110

Reaction equation

Participants

RoleNameHCIDCharge
ReactantIndomethacinHCID 3715—
Reactant4-Amino-2-(trifluoromethyl)benzonitrileHCID 522170—
Reagent2,6-LutidineHCID 7937—
ReagentPyBOPHCID 2724699—
SolventAcetonitrileHCID 6342—
ProductHCID 178487187HCID 17848718711.84%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

DOI10.26434/chemrxiv
Source datasetAniline amide coupling reaction
ORD IDord-f0ef8f215f5445f6b5476d4c0e7bda60
Source noteAniline amide coupling reaction