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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1273140Generated: October 31, 2026

Indomethacin → HCID 178487187, compound

https://huagongshe.com/reaction/1273140

Reaction equation

Participants

RoleNameHCIDCharge
ReactantIndomethacinHCID 3715—
Reactant4-Amino-2-(trifluoromethyl)benzonitrileHCID 522170—
ReagentDiisopropylethylamineHCID 81531—
ReagentHCID 178483998HCID 178483998—
SolventDimethylformamideHCID 6228—
ProductHCID 178487187HCID 17848718720.17%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

DOI10.26434/chemrxiv
Source datasetAniline amide coupling reaction
ORD IDord-38e2fd7fb7a24a75acd15025b3bb7655
Source noteAniline amide coupling reaction