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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1273142Generated: October 30, 2026

Indomethacin → HCID 178487187, compound

https://huagongshe.com/reaction/1273142

Reaction equation

Participants

RoleNameHCIDCharge
ReactantIndomethacinHCID 3715—
Reactant4-Amino-2-(trifluoromethyl)benzonitrileHCID 522170—
Reagent2,6-LutidineHCID 7937—
ReagentDiphenylphosphinic chlorideHCID 73910—
SolventTetrahydrofuranHCID 8028—
ProductHCID 178487187HCID 17848718714.55%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

DOI10.26434/chemrxiv
Source datasetAniline amide coupling reaction
ORD IDord-15c2d586022f418b8c5041c4b73da38e
Source noteAniline amide coupling reaction