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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1273220Generated: November 3, 2026

Indomethacin → HCID 178486287, compound

https://huagongshe.com/reaction/1273220

Reaction equation

Participants

RoleNameHCIDCharge
ReactantIndomethacinHCID 3715—
Reactant4-Amino-N-methylbenzenemethanesulfonamideHCID 2778131—
ReagentDiisopropylethylamineHCID 81531—
ReagentBis(2-oxo-3-oxazolidinyl)phosphinic chlorideHCID 152842—
SolventAcetonitrileHCID 6342—
ProductHCID 178486287HCID 17848628740.83%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

DOI10.26434/chemrxiv
Source datasetAniline amide coupling reaction
ORD IDord-4b9fe37dc1bc441296278735d1eeea05
Source noteAniline amide coupling reaction