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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1273344Generated: October 30, 2026

Indomethacin → HCID 178487182, compound

https://huagongshe.com/reaction/1273344

Reaction equation

Participants

RoleNameHCIDCharge
ReactantIndomethacinHCID 3715—
Reactant1,3-Diphenyl-1H-pyrazol-5-amineHCID 199969—
ReagentDiphenylphosphinic chlorideHCID 73910—
ReagentDiisopropylethylamineHCID 81531—
SolventDimethylformamideHCID 6228—
ProductHCID 178487182HCID 17848718225.76%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

DOI10.26434/chemrxiv
Source datasetAniline amide coupling reaction
ORD IDord-00fef3fd30f34d19b3e82d68b06fb7e4
Source noteAniline amide coupling reaction