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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1273345Generated: October 30, 2026

Indomethacin → HCID 178487182, compound

https://huagongshe.com/reaction/1273345

Reaction equation

Participants

RoleNameHCIDCharge
ReactantIndomethacinHCID 3715—
Reactant1,3-Diphenyl-1H-pyrazol-5-amineHCID 199969—
Reagent1-MethylimidazoleHCID 1390—
Reagent6-Cyano-N,N,2-trimethyl-7-oxo-4,8-dioxa-2,5-diazadec-5-en-3-iminium hexafluorophosphateHCID 57348955—
SolventTetrahydrofuranHCID 8028—
ProductHCID 178487182HCID 17848718223.06%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

DOI10.26434/chemrxiv
Source datasetAniline amide coupling reaction
ORD IDord-e17ab31b658941b49802fc61f91b1f57
Source noteAniline amide coupling reaction