Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1273348Generated: October 31, 2026

Indomethacin → HCID 178487182, compound

https://huagongshe.com/reaction/1273348

Reaction equation

Participants

RoleNameHCIDCharge
ReactantIndomethacinHCID 3715—
Reactant1,3-Diphenyl-1H-pyrazol-5-amineHCID 199969—
ReagentDiisopropylethylamineHCID 81531—
Reagent6-Cyano-N,N,2-trimethyl-7-oxo-4,8-dioxa-2,5-diazadec-5-en-3-iminium hexafluorophosphateHCID 57348955—
SolventTetrahydrofuranHCID 8028—
ProductHCID 178487182HCID 178487182-0.8%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

DOI10.26434/chemrxiv
Source datasetAniline amide coupling reaction
ORD IDord-33b15ffa116d4aa6b2295ed2daa4cd66
Source noteAniline amide coupling reaction