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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1273352Generated: October 31, 2026

Indomethacin → HCID 178487182, compound

https://huagongshe.com/reaction/1273352

Reaction equation

Participants

RoleNameHCIDCharge
ReactantIndomethacinHCID 3715—
Reactant1,3-Diphenyl-1H-pyrazol-5-amineHCID 199969—
ReagentDiisopropylethylamineHCID 81531—
Reagent6-Cyano-N,N,2-trimethyl-7-oxo-4,8-dioxa-2,5-diazadec-5-en-3-iminium hexafluorophosphateHCID 57348955—
SolventAcetonitrileHCID 6342—
ProductHCID 178487182HCID 17848718210.25%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

DOI10.26434/chemrxiv
Source datasetAniline amide coupling reaction
ORD IDord-075ead0e90de47ebac506165f97e97ba
Source noteAniline amide coupling reaction