反应详情

To 121 g of 2,5-dimethylaniline, 100 g of sulfuric acid (d=1.84) was gradually added dropwise and the mixture was heated at 220° to 230° C. on an oil bath for 5 hours. To the reaction mixture, 2 l of an 1 N aqueous potasium hydroxide solution was added and the mixture was stirred with heating. After filtering the mixture while hot, 1 kg of hydrochloric acid (d=1.18) was added to the filtrate. The crystals thus precipitated were collected by filtration and washed with 1 l of acetone.

1. temperaturethe mixture was heated at 220° to 230° C. on an oil bath for 5 hours
2. temperaturewith heating
3. filtrationAfter filtering the mixture while hot, 1 kg of hydrochloric acid (d=1.18)
4. additionwas added to the filtrate
5. customThe crystals thus precipitated
6. filtrationwere collected by filtration
7. washwashed with 1 l of acetone