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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1273385Generated: October 30, 2026

Indomethacin → HCID 178487184, compound

https://huagongshe.com/reaction/1273385

Reaction equation

Participants

RoleNameHCIDCharge
ReactantIndomethacinHCID 3715—
Reactant2-Bromo-4,6-dimethylanilineHCID 170579—
Reagent1-MethylimidazoleHCID 1390—
ReagentMethanaminium, N-((dimethylamino)(3H-1,2,3-triazolo(4,5-b)pyridin-3-yloxy)methylene)-N-methyl-, hexafluorophosphate(1-) (1:1)HCID 9886157—
SolventAcetonitrileHCID 6342—
ProductHCID 178487184HCID 17848718416.33%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

DOI10.26434/chemrxiv
Source datasetAniline amide coupling reaction
ORD IDord-24a48ad99189463a9f09651e44b3f4c2
Source noteAniline amide coupling reaction