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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1273497Generated: October 31, 2026

Indomethacin → HCID 178487188, compound

https://huagongshe.com/reaction/1273497

Reaction equation

Participants

RoleNameHCIDCharge
ReactantIndomethacinHCID 3715—
Reactant3-Amino-4-chlorobenzonitrileHCID 104464—
Reagent1-MethylimidazoleHCID 1390—
ReagentPyBOPHCID 2724699—
SolventDimethylformamideHCID 6228—
ProductHCID 178487188HCID 1784871885.42%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

DOI10.26434/chemrxiv
Source datasetAniline amide coupling reaction
ORD IDord-3e23a8d1d5124decbae5a1aa297011e5
Source noteAniline amide coupling reaction