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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1273528Generated: October 31, 2026

Indomethacin → HCID 178487188, compound

https://huagongshe.com/reaction/1273528

Reaction equation

Participants

RoleNameHCIDCharge
ReactantIndomethacinHCID 3715—
Reactant3-Amino-4-chlorobenzonitrileHCID 104464—
ReagentDiphenylphosphinic chlorideHCID 73910—
ReagentDiisopropylethylamineHCID 81531—
SolventTetrahydrofuranHCID 8028—
ProductHCID 178487188HCID 17848718838.28%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

DOI10.26434/chemrxiv
Source datasetAniline amide coupling reaction
ORD IDord-6038281d348849b2bfd4d1693ee02c5a
Source noteAniline amide coupling reaction