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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1273545Generated: October 29, 2026

Indomethacin → HCID 178487188, compound

https://huagongshe.com/reaction/1273545

Reaction equation

Participants

RoleNameHCIDCharge
ReactantIndomethacinHCID 3715—
Reactant3-Amino-4-chlorobenzonitrileHCID 104464—
Reagent1-MethylimidazoleHCID 1390—
Reagent6-Cyano-N,N,2-trimethyl-7-oxo-4,8-dioxa-2,5-diazadec-5-en-3-iminium hexafluorophosphateHCID 57348955—
SolventDimethylformamideHCID 6228—
ProductHCID 178487188HCID 17848718814.15%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

DOI10.26434/chemrxiv
Source datasetAniline amide coupling reaction
ORD IDord-f31cafa98904414daac3f36c647e7553
Source noteAniline amide coupling reaction