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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1273581Generated: November 3, 2026

Indomethacin → HCID 178487189, compound

https://huagongshe.com/reaction/1273581

Reaction equation

Participants

RoleNameHCIDCharge
ReactantIndomethacinHCID 3715—
Reactant2-Methyl-4-nitroanilineHCID 7441—
Reagent1-MethylimidazoleHCID 1390—
ReagentMethanaminium, N-((dimethylamino)(3H-1,2,3-triazolo(4,5-b)pyridin-3-yloxy)methylene)-N-methyl-, hexafluorophosphate(1-) (1:1)HCID 9886157—
SolventDimethylformamideHCID 6228—
ProductHCID 178487189HCID 1784871892.45%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

DOI10.26434/chemrxiv
Source datasetAniline amide coupling reaction
ORD IDord-6b46b18e918842fc89125415838c22dc
Source noteAniline amide coupling reaction