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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1273621Generated: October 29, 2026

Indomethacin → HCID 178487189, compound

https://huagongshe.com/reaction/1273621

Reaction equation

Participants

RoleNameHCIDCharge
ReactantIndomethacinHCID 3715—
Reactant2-Methyl-4-nitroanilineHCID 7441—
Reagent1-MethylimidazoleHCID 1390—
ReagentDiphenylphosphinic chlorideHCID 73910—
SolventTetrahydrofuranHCID 8028—
ProductHCID 178487189HCID 1784871893.4%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

DOI10.26434/chemrxiv
Source datasetAniline amide coupling reaction
ORD IDord-7d5efe0c52784cf3a6ea57aae35a96f2
Source noteAniline amide coupling reaction