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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1273632Generated: November 1, 2026

Indomethacin → HCID 178487189, compound

https://huagongshe.com/reaction/1273632

Reaction equation

Participants

RoleNameHCIDCharge
ReactantIndomethacinHCID 3715—
Reactant2-Methyl-4-nitroanilineHCID 7441—
ReagentDiphenylphosphinic chlorideHCID 73910—
ReagentDiisopropylethylamineHCID 81531—
SolventDimethylformamideHCID 6228—
ProductHCID 178487189HCID 1784871891.69%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

DOI10.26434/chemrxiv
Source datasetAniline amide coupling reaction
ORD IDord-a6eeeb95e34e41619ebead6c2be1d09b
Source noteAniline amide coupling reaction