Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1273636Generated: November 2, 2026

Indomethacin → HCID 178487189, compound

https://huagongshe.com/reaction/1273636

Reaction equation

Participants

RoleNameHCIDCharge
ReactantIndomethacinHCID 3715—
Reactant2-Methyl-4-nitroanilineHCID 7441—
ReagentDiisopropylethylamineHCID 81531—
Reagent6-Cyano-N,N,2-trimethyl-7-oxo-4,8-dioxa-2,5-diazadec-5-en-3-iminium hexafluorophosphateHCID 57348955—
SolventTetrahydrofuranHCID 8028—
ProductHCID 178487189HCID 17848718910.69%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

DOI10.26434/chemrxiv
Source datasetAniline amide coupling reaction
ORD IDord-e06ef685ee7a406094edb99ad8e3206a
Source noteAniline amide coupling reaction