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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1273813Generated: October 29, 2026

Indomethacin → HCID 178487185, compound

https://huagongshe.com/reaction/1273813

Reaction equation

Participants

RoleNameHCIDCharge
ReactantIndomethacinHCID 3715—
ReactantDiisopropylanilineHCID 32484—
Reagent1-MethylimidazoleHCID 1390—
ReagentDiphenylphosphinic chlorideHCID 73910—
SolventTetrahydrofuranHCID 8028—
ProductHCID 178487185HCID 17848718537.93%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

DOI10.26434/chemrxiv
Source datasetAniline amide coupling reaction
ORD IDord-7bef8f4e37c34758aff75c6ee548fa1e
Source noteAniline amide coupling reaction