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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1273924Generated: November 3, 2026

Indomethacin → HCID 178487186, compound

https://huagongshe.com/reaction/1273924

Reaction equation

Participants

RoleNameHCIDCharge
ReactantIndomethacinHCID 3715—
ReactantHCID 178507598HCID 178507598—
ReagentDiisopropylethylamineHCID 81531—
Reagent6-Cyano-N,N,2-trimethyl-7-oxo-4,8-dioxa-2,5-diazadec-5-en-3-iminium hexafluorophosphateHCID 57348955—
SolventTetrahydrofuranHCID 8028—
ProductHCID 178487186HCID 17848718617.68%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

DOI10.26434/chemrxiv
Source datasetAniline amide coupling reaction
ORD IDord-837687cb38c94b38a029a28383cf126a
Source noteAniline amide coupling reaction