化工社化工社 化学情報印刷レポート · 研究参考用
Thionyl Chloride → 7-Methylsulfamoyl-1,4-benzodioxane-5-carbonyl chloride
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Thionyl Chloride | HCID 24386 | — |
| 反応物 | 2,3-Dihydro-7-(N-methylsulphamoyl)-1,4-benzodioxin-5-carboxylic acid | HCID 6455317 | — |
| 溶媒 | Chloroform | HCID 6212 | — |
| 生成物 | 7-Methylsulfamoyl-1,4-benzodioxane-5-carbonyl chloride | HCID 20544720 | — |
反応手順
176.5 g of thionyl chloride were introduced into a balloon flask provided with a condenser. Then, in portions, 135 g of 7-methylsulfamoyl-1,4-benzodioxane-5-carboxylic acid were added under heating at 40°-45° C. The mixture was heated under reflux and then treated with 250 cm3 chloroform. The precipitate was dried off and washed with chloroform.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04255580 |
| 出典データセット | uspto-grants-1981_03 |
| ORD ID | ord-7c5079e88a35498fb213127bef9295c0 |
| 出典メモ | uspto-grants-1981_03 |